Cells become zombies when the ends of their chromosomes are damaged – a tactic both helpful and harmful for health

The Research Brief is a short take about interesting academic work.

The big idea

Damage to the ends of your chromosomes can create “zombie cells” that are still alive but can’t function, according to our recently published study in Nature Structural and Molecular Biology.

When cells prepare to divide, their DNA is tightly wound around proteins to form chromosomes that provide structure and support for genetic material. At the ends of these chromosomes are repetitive stretches of DNA called telomeres that form a protective cap to prevent damage to the genetic material. However, telomeres shorten each time a cell divides. This means that as cells divide more and more as you age, your telomeres become increasingly shorter and more likely to lose their ability to protect your DNA.

Tujuan kami adalah menciptakan tempat yang aman dan menarik bagi pengguna untuk terhubung melalui minat dan kegemaran. Untuk meningkatkan pengalaman komunitas, kami menangguhkan sementara fitur komentar artikel